UGT2B7_−161C>T Polymorphism Is Associated With Lamotrigine Concentration-to-Dose Ratio in a Multivariate Study
UGT2B7_−161C>T Polymorphism Is Associated With Lamotrigine Concentration-to-Dose Ratio in a Multivariate Study
María Blanca Sánchez,J. Herranz,7 Authors,J. Armijo
2010 · DOI: 10.1097/FTD.0b013e3181ceecc6
Therapeutic Drug Monitoring · 63 Citations
TLDR
UGT2B7_−161C>T polymorphism is significantly associated with LTG-CDR when comedication with other antiepileptic drugs and patient age are taken into account in a multivariate analysis, and this polymorphism was not found in the bivariate or the multivariate studies.